Riluzole, RP-54274, PK-26124, Rilutek
利鲁唑Chemical Name: 2-Amino-6-(trifluoromethoxy)benzothiazole; 6-(Trifluoromethoxy)benzothiazol-2-amine
CAS No. 1744-22-5
项目整合开发状态: Launched-1996
项目研究机构: Aventis Pharma (Originator)
合成路线:By condensation of 4-(trifluoromethoxy)aniline (I) with potassium thiocyanate (II) by means of Br2 in acetic acid.
📌 参考资料/链接:
参考文献标题:New medicament containing 2-amino-6-trifluoromethoxybenzothiazole
文献作者:Mizoule,J.(Pharmindustrie)
参考来源:EP 0050551
📄 详细内容
合成路线:By condensation of 4-(trifluoromethoxy)aniline (I) with potassium thiocyanate (II) by means of Br2 in acetic acid.
参考文献标题:Riluzole
文献作者:Castar,J.; Rabasseda,X.; Mealy,N.
参考来源:Drugs Fut 1994,19(10),920
产品链接: CAS No. 1744-22-5››