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项目整合精选>>>Ansamycin, Rifabutin, LM-427, Ansatipine, Ansatipin, Mycobutin
Ansamycin, Rifabutin, LM-427, Ansatipine, Ansatipin, Mycobutin
利福布汀Chemical Name: (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-16-Acetoxy-6,18,20-tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethylspiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione; 1',4-Didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxorifamycin XIV; N-(2-Methylpropyl)spiropiperidylrifamycin S; 4-N-Isobutylspiropiperidylrifamycin S
CAS No. 72559-06-9
项目整合开发状态: Launched-1992
项目研究机构: Pfizer (Originator)
合成路线:By reaction of 3-amino-4-deoxo-4-iminorifamycin S (I) with N-(2-methylpropyl)-4-piperidone (II) in methylene chloride.
📌 参考资料/链接：
参考文献标题:Rifamycin compounds
文献作者:Marsili,L.; Rossetti,V.; Pasqualucci,C.(Archifar Laboratori Chimico Farmacologici SpA)
参考来源:BE 0870570; DE 2825445; FR 2426690; GB 1603127; JP 8007203; NL 7806659
📄 详细内容
合成路线:By reaction of 3-amino-4-deoxo-4-iminorifamycin S (I) with N-(2-methylpropyl)-4-piperidone (II) in methylene chloride.
参考文献标题:Rifabutin
文献作者:Castar,J.; Serradell,M.N.
参考来源:Drugs Fut 1985,10(5),405
产品链接: CAS No. 72559-06-9››