Edaravone, MCI-186, Radicut
依达拉奉Chemical Name: 3-Methyl-1-phenyl-2-pyrazolin-5-one
CAS No. 89-25-8, 94489-23-3 (NH3 salt)
项目整合开发状态: Launched-2001
项目研究机构: Mitsubishi Pharma (Originator)
合成路线:By direct cyclization of phenylhydrazine (I) with ethyl acetoacetate (II) in refluxing ethanol.
📌 参考资料/链接：
参考文献标题:Prophylactic and therapeutic agent for circulatory disorders
文献作者:Nishi,H.; Watanabe,T.; Yuki,S.; Morinaka,Y.; Iseki,K.; Sakurai,H.(Mitsubishi Chemical Corp.)
参考来源:EP 0208874; JP 1987108814; US 4857542
📄 详细内容
合成路线:By direct cyclization of phenylhydrazine (I) with ethyl acetoacetate (II) in refluxing ethanol.
参考文献标题:Edaravone
文献作者:Graul,A.; Castar,J.
参考来源:Drugs Fut 1996,21(10),1014
产品链接: CAS No. 89-25-8››