Epinastine
依匹斯汀Chemical Name: 3-Amino-9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepine
CAS No. 80012-43-7
项目整合开发状态: Launched
项目研究机构: Boehringer Ingelheim (Originator)
合成路线:By cyclization of 6-(aminomethyl)-6,11-dihydro-5H-dibenz[b,e]azepine (I) with cyanogen bromide (II) in THF,followed by a treatment with NaOH and acidification with HCl in ether.
📌 参考资料/链接：
参考文献标题:Fused dibenzo imidazolo compounds,compositions and use
文献作者:Walther,G.; Schneider,C.S,,Weber,K.-H.; Fuegner,A.(Boehringer Ingelheim GmbH)
参考来源:DE 3008944
📄 详细内容
合成路线:By cyclization of 6-(aminomethyl)-6,11-dihydro-5H-dibenz[b,e]azepine (I) with cyanogen bromide (II) in THF,followed by a treatment with NaOH and acidification with HCl in ether.
参考文献标题:Epinastine Hydrochloride
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1987,12(12),1106
产品链接: CAS No. 80012-43-7››