Elliptinium acetate, NSC-264137, HME, Celiptium
依利醋铵 6H-吡啶[4,3-b]卡巴唑铵,9-羟基-2,5,11-三甲基-,碘化物(1:1) Chemical Name: 9-Hydroxy-2-methylellipticinium acetate; 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium acetate
CAS No. 58337-35-2, 58447-24-8 (iodide)
项目整合开发状态: Launched-1983
项目研究机构: Sanofi-Aventis (Originator)
合成路线:The iodide is formed as follows: 9-Methoxy-ellipticine (I) (extracted from Ochrosia maculata) is demethylated by refluxing with pyridine hydrochloride to give 9-hydroxy-ellipticine (II),which is then treated with methyl iodide in DMF at room temperature.
📌 参考资料/链接：
参考文献标题:Derivatives of 9-hydroxy-ellipticine and a process fo their preparation
文献作者:Le Pecq,J.B.; et al.(ANVAR (Agence Natl.Valor.Rech.))
参考来源:CH 616937; DE 2618223; FR 2308365; GB 1508388
📄 详细内容
合成路线:The iodide is formed as follows: 9-Methoxy-ellipticine (I) (extracted from Ochrosia maculata) is demethylated by refluxing with pyridine hydrochloride to give 9-hydroxy-ellipticine (II),which is then treated with methyl iodide in DMF at room temperature.
参考文献标题:NSC-264137
文献作者:Woodman,R.J.
参考来源:Drugs Fut 1979,4(4),267
产品链接: CAS No. 58337-35-2›› 产品链接: CAS No.58447-24-8››