Xorphanol, TR-5379
佐尔啡诺 (8beta)-17-(环丁基甲基)-8-甲基-6-亚甲基吗喃-3-醇甲烷磺酸盐(1:1) Chemical Name: 17-Cyclobutylmethyl-3-hydroxy-6-methylene-8beta-methylmorphinan
CAS No. 77287-89-9, 77287-90-2 (mesylate)
项目整合开发状态: Phase III
项目研究机构: Pars (Originator)
合成路线:By a Wittig condensation of 17-cyclobutylmethyl-3-hydroxy-8beta-methyl morphinan-6-one (I) with triphenylmethylenephosphorane in DMSO.
📌 参考资料/链接：
参考文献标题:17-Cyclobutylmethyl-3-hydroxy-beta-methyl-6-methylene morphinane,and methods of treating pain with them
文献作者:Kotick,M.P.; Polazzi,J.O.(Bayer Corp.)
参考来源:CA 1128508; EP 0027925; ES 8107222; US 4259329
📄 详细内容
合成路线:By a Wittig condensation of 17-cyclobutylmethyl-3-hydroxy-8beta-methyl morphinan-6-one (I) with triphenylmethylenephosphorane in DMSO.
参考文献标题:TR-5379
文献作者:Serradell,M.N.; Blancafort,P.; Castar,J.
参考来源:Drugs Fut 1982,7(1),40
产品链接: CAS No. 77287-89-9›› 产品链接: CAS No.77287-90-2››