Ipsalazide(Rec INN, BAN), BX-650A
伊普柳氮Chemical Name: (E)-p-[(3-Carboxy-4-hydroxyphenyl)azo]hippuric acid; (E)-5-[[4-[(Carboxymethyl)carbamoyl]phenyl]azo]salicylic acid; (E)-5-[[4-[[(Carboxymethyl)amino]carbonyl]phenyl]azo]-2-hydroxybenzoic acid
CAS No. 80573-03-1
项目整合开发状态: Biological Testing
项目研究机构: Biorex Laboratories (Originator)
合成路线:The diazotation of 4-aminohippuric acid (I) with NaNO2 and HCl gives the corresponding diazonium salt (II),which is then condensed with salicylic acid.
📌 参考资料/链接：
参考文献标题:Balsalazide and Ipsalazide
文献作者:Castar,J.; Serradell,M.N.
参考来源:Drugs Fut 1984,9(5),313
📄 详细内容
合成路线:The diazotation of 4-aminohippuric acid (I) with NaNO2 and HCl gives the corresponding diazonium salt (II),which is then condensed with salicylic acid.
参考文献标题:2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
文献作者:Chan,R.P.K.
参考来源:DE 3128819; FR 2493312; JP 57053449; US 4412992
产品链接: CAS No. 80573-03-1››