Triclabendazole, CGA-89317, Fasinex
三氯苯达唑Chemical Name: 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-benzimidazole
CAS No. 68786-66-3
项目整合开发状态: Biological Testing
项目研究机构:
合成路线:The cyclization of 4-chloro-5-(2,3-dichlorophenoxy)-o-phenylenediamine (I) with carbon disulfide gives 5-chloro-6-(2,3-dichlorophenoxy)-2H-1,3-dihydrobenzimidazole-2-thione (II),which is methylated with methyl iodide and KOH in ethanol - water
📌 参考资料/链接：
参考文献标题:Triclabendazole
文献作者:Serradell,M.N.; Castar,J.; Thorpe,P.J.
参考来源:Drugs Fut 1984,9(8),593
📄 详细内容
合成路线:The cyclization of 4-chloro-5-(2,3-dichlorophenoxy)-o-phenylenediamine (I) with carbon disulfide gives 5-chloro-6-(2,3-dichlorophenoxy)-2H-1,3-dihydrobenzimidazole-2-thione (II),which is methylated with methyl iodide and KOH in ethanol - water
参考文献标题:
文献作者:Gallay,J.J.; Kuehne,M.E.; Meyer,A.; Rechsteiner,O.; Schellenbaum,M.(Ciba Geigy A.-G.)
参考来源:DE 2815621; FR 2387220; US 4197307
产品链接: CAS No. 68786-66-3››