3-n-Butylphthalide, NBP
丁苯酞3-正丁基苯酞Chemical Name: (?-3-Butyl-2-benzofuran-1(3H)-one; (?-3-Butyl-1(3H)-isobenzofuranone
CAS No. 6066-49-5, 194085-46-6 ((R)-isomer), 3413-15-8 ((S)-isomer)
项目整合开发状态: Phase II
项目研究机构: Chinese Academy of Medical Sciences (Originator), Institute of Materia Medica (Originator)
合成路线:Ftalic anhydride (I) id treated with butyric anhydride (II) and sodium butyrate to obtain lactone (IV),which is hydrogenated to target compound by means H2 Nickel Raney.
📌 参考资料/链接：
参考文献标题:3-n-Butylphthalide
文献作者:Wang,X.-W.
参考来源:Drugs Fut 2000,25(1),16
📄 详细内容
合成路线:Ftalic anhydride (I) id treated with butyric anhydride (II) and sodium butyrate to obtain lactone (IV),which is hydrogenated to target compound by means H2 Nickel Raney.
参考文献标题:Isolation and determination of active components of Apium graveolens
文献作者:Chen,Y.W.; Yang,J.S.
参考来源:Chin Pharm Bull 1984,19670
合成路线:Ftalic anhydride (I) id treated with butyric anhydride (II) and sodium butyrate to obtain lactone (IV),which is hydrogenated to target compound by means H2 Nickel Raney.
参考文献标题:Studies on chemical constituents of volatile oil from Apium graveolens seeds
文献作者:Fang,H.J.; Chen,Y.W.; Sun,S.W.; Hu,Q.; Yang,J.S.
参考来源:Chin Drug Analyt J 1984,4205
产品链接: CAS No. 6066-49-5›› 产品链接: CAS No.3413-15-8››