Bufuralol, Ro-34787
丁呋洛尔Chemical Name: alpha-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol
CAS No. 54340-62-4
项目整合开发状态: Phase III
项目研究机构: Roche (Originator), Helsinn (Licensee)
合成路线:The condensation of tert-butylamine (II) with 2-(2-chloro-1-hydroxyethyl)-7-ethylbenzofuran (I) or with 2-epoxyehtyl-7-ethylbenzofuran (III) in refluxing ethanol.
📌 参考资料/链接：
参考文献标题:Verfahren zur Herstellung von Benzofuranderivaten
文献作者:Osbon,J.M.; et al.(Bristol-Myers Squibb Co.)
参考来源:CH 498109; DE 1543653; FR 1479002; FR 6011M; GB 1106057; NL 6606441
📄 详细内容
合成路线:The condensation of tert-butylamine (II) with 2-(2-chloro-1-hydroxyethyl)-7-ethylbenzofuran (I) or with 2-epoxyehtyl-7-ethylbenzofuran (III) in refluxing ethanol.
参考文献标题:Bufuralol
文献作者:Castar,J.; Prous,J.R.
参考来源:Drugs Fut 1976,1(1),11
产品链接: CAS No. 54340-62-4››