Dihydroqinghaosu, Artenimol, Dihydroartemisinin, DHA, Cotecxin
α-双氢青蒿素 双氢青蒿素 Chemical Name: (3R,5aS,6R,8aS,9R,10RS,12R,12aR)-Decahydro-10-hydroxy-3,6,9-trimethyl-3, 12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepine
CAS No. 81496-81-3 (alpha-isomer), 71939-50-9 (beta-isomer)
项目整合开发状态: Launched
项目研究机构: Shanghai Institute Materia Medica (Originator), Beijing COTEC (Marketer)
合成路线:The title lactol derivative was prepared by reduction of the lactone function of artemisinin (quinghaosu) (I) by means of NaBH4 in MeOH.
📌 参考资料/链接：
参考文献标题:173.The chemistry of drugs.Part IV.Configurations of antimalarials derived from qinghaosu: Dihydroqinghaosu,artemether,and artesunic acid
文献作者:Lu,X.-D.; et al.
参考来源:Helv Chim Acta 1984,67(6),1515
📄 详细内容
合成路线:The title lactol derivative was prepared by reduction of the lactone function of artemisinin (quinghaosu) (I) by means of NaBH4 in MeOH.
参考文献标题:Stereoselective synthesis and antimalarial activity of alpha-artelinic acid from artemisinin
文献作者:Vishwakarma,R.A.; Mehrotra,R.; Tripathi,R.C.; Dutta,G.P.
参考来源:J Nat Prod 1992,55(8),1142
产品链接: CAS No. 81496-81-3›› 产品链接: CAS No.71939-50-9››