(-)-SK&F-10047, SK&F-10047
N-烯丙去甲间唑新Chemical Name: (-)-2'-Hydroxy-5,9-dimethyl-2-allyl-6,7-benzomorphan; (-)-(2R,6R,11R)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol
CAS No. 14198-28-8, 74957-58-7 (HCl), 59985-34-1 (lactate)
项目整合开发状态: Preclinical
项目研究机构: GlaxoSmithKline (Originator)
合成路线:By condensation of 2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (I) with allyl bromide (II) by means of NaHCO3 in refluxing ethanol.
📌 参考资料/链接：
参考文献标题:Novel N-allyl and N-propargyl benzmorphan derivs.
文献作者:Gordon,M.; Lafferty,J.J.(SmithKline Beecham Corp.)
参考来源:US 4048178
📄 详细内容
合成路线:By condensation of 2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (I) with allyl bromide (II) by means of NaHCO3 in refluxing ethanol.
参考文献标题:SKF-10,047
文献作者:Serradell,M.N.; Castar,J.; Paton,D.M.; Blancafort,P.
参考来源:Drugs Fut 1983,8(5),439
产品链接: CAS No. 14198-28-8›› 产品链接: CAS No.74957-58-7››