Andolast, CR-2039

N-4-(1H-四唑-5-基)苯基-4-(1H-四唑-5-基)苯甲酰胺Chemical Name: 4-(1H-Tetrazol-5-yl)-N-[4-(1H-tetrazol-5-yl)phenyl]benzamide
CAS No. 132640-22-3
项目整合开发状态: Phase II
项目研究机构: Rotta (Originator)
合成路线:Coupling between 4-cyanobenzoyl chloride (I) and 4-aminobenzonitrile (II) in the presence of Et3N afforded the corresponding amide (III).The dicyano compound (III) was then treated with sodium azide and ammonium chloride in hot DMF to produce the title bis-tetrazolyl derivative.