SB-237376

N-[3-[2-(3,4-二甲氧基苯基)乙基氨基]丙基]-4-硝基苯甲酰盐酸盐Chemical Name: N-[3-[2-(3,4-Dimethoxyphenyl)ethylamino]propyl]-4-nitrobenzamide hydrochloride
CAS No. 179258-62-9, 179258-59-4 (free base)
项目整合开发状态: Discontinued
项目研究机构: GlaxoSmithKline (Originator)
合成路线:The reaction of 4-nitrobenzoyl chloride (I) with 3-chloropropylamine (II) by menas of triethylamine in dichloromethane gives the corresponding amide (III),which is then condensed with 2-(3,4-dimethoxyphenyl)ethylamine (IV) by means of triethylamine in refluxing dichloromethane.