SK-946
N-[2-(1-氮杂双环[3.3.0]辛烷-5-基)乙基]-2-硝基苯胺富马酸盐Chemical Name: N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate
CAS No. 167889-18-1, 167889-05-6 (free base), 167889-17-0 (monoHCl), 167889-19-2 (monomaleate)
项目整合开发状态: Preclinical
项目研究机构: Sanwa (Originator)
合成路线:By condensation of 2-chloronitrobenzene (I) with 5-(2-aminoethyl)-1-azabicyclo[3.3.0]octane (II) in refluxing pyridine.
📌 参考资料/链接：
参考文献标题:1-Azabicyclo[3.3.0]octane derivs.and their use
文献作者:Baba,Y.; Suzuki,T.; Hirooka,K.; Kurono,M.; Sawai,K.(Sanwa Kagaku Kenkyusho Co.,Ltd.)
参考来源:EP 0647642; US 5530138
📄 详细内容
合成路线:By condensation of 2-chloronitrobenzene (I) with 5-(2-aminoethyl)-1-azabicyclo[3.3.0]octane (II) in refluxing pyridine.
参考文献标题:Synthesis and muscarinic activity of novel aniline derivatives with a 1-azabicyclo[3.3.0]octane moiety
文献作者:Suzuki,T.; Oka,M.; Maeda,K.; Furusawa,K.; Uesaka,H.; Kataoka,T.
参考来源:Chem Pharm Bull 1999,47(1),28
产品链接: CAS No. 167889-18-1››