BW-540C
N-[(1-甲基-5-苯基-2,3-二氢-1H-1,4-苯并二氮卓-2-基)甲基]苯酰胺二盐酸Chemical Name: 4,5-Dihydro-N-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 3-Methylamino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Methylamino-1-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-pyrazole
CAS No. 83908-32-1, 83908-33-2 (monoHCl)
项目整合开发状态: Biological Testing
项目研究机构: GlaxoSmithKline (Originator)
合成路线:The reaction of 3-amino-1-(3-trifluoromothylphenyl)-2-pyrazoline (I) with formic acid gives the corresponding N-formyl derivative (II),which is then reduced with LiAlH4 in ether.
📌 参考资料/链接：
参考文献标题:Pyrazoline derivates,processes for their preparation and pharmaceutical formulations containing them
文献作者:Copp,F.C.; Caldwell,A.G.; Collard,D.(Glaxo Wellcome plc)
参考来源:DE 3149710; EP 0055418; FR 2496100; GB 2093832
📄 详细内容
合成路线:The reaction of 3-amino-1-(3-trifluoromothylphenyl)-2-pyrazoline (I) with formic acid gives the corresponding N-formyl derivative (II),which is then reduced with LiAlH4 in ether.
参考文献标题:BW-540C
文献作者:Castar,J.; Serradell,M.N.
参考来源:Drugs Fut 1985,10(5),374
产品链接: CAS No. 83908-32-1››