FR-115224, FK-224
N-(N(2)-(N-(N-(N-(2,3-二去氢-N-甲基-N-(N-(3-(2-戊基苯基)-丙酰基)-L-苏氨酰)酪氨酰-L-亮氨酰)-D-苯丙氨酰)-L-别-苏氨酰)-L-天冬氨酰胺酰))-L-丝氨酸-epsilon-内酯Chemical Name: N-[3-(2-Pentylphenyl)propionyl]-threonyl-N-methyl-2,3-dehydrotyrosyl-leucyl-D-phenylalanyl-allo-threonyl-asparaginyl-serine C-1.7-O-3.1 lactone
CAS No. 125787-94-2
项目整合开发状态: Phase II
项目研究机构: Fujisawa (Originator)
合成路线:Catalytic hydrogenation of WS9326A gave tetrahydro-WS9326A (FK224).
📌 参考资料/链接：
参考文献标题:FK-224
文献作者:Tasaka,K.
参考来源:Drugs Fut 1992,17(8),679
📄 详细内容
合成路线:Catalytic hydrogenation of WS9326A gave tetrahydro-WS9326A (FK224).
参考文献标题:WS9326A,a novel tachykinin antagonist isolated from Streptomyces violacenoniger No.9326.I.Taxonomy,fermentation,isolation,physico-chemical properties and biological activities
文献作者:Hayashi,K.; Hashimoto,M.; Shigematsu,N.; Nishikawa,M.; Ezaki,M.; Yamashita,M.; Kiyoto,S.; Okuhara,M.; Kohsaka,M.; Imanaka,H.
参考来源:J Antibiot 1992,45(7),1055-63
产品链接: CAS No. 125787-94-2››