合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:N4-Acylarabinonucleosides
文献作者:Ishida,T.; et al.(Asahi Chemical Industry Co.,Ltd.)
参考来源:DE 2461862
合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:Palmitoyl/Stearoyl Ara-C
文献作者:Cabanillas,F.; Castar,J.
参考来源:Drugs Fut 1980,5(12),617
合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:
文献作者:Ishida,T.; et al.
参考来源:JP 7707974
合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:
文献作者:Ishida,T.; et al.
参考来源:JP 7632573
合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:
文献作者:Ishida,T.; et al.
参考来源:JP 7648679
合成路线:This compound can be obtained in two different ways:1) By condensation of 1-beta-D-arabinofuranosylcytosine (I) with palmitic anhydride (II) in hot dioxane.2) By acylation of cytidine (III) with palmitic anhydride (II) in hot dioxane to yield N4-palmitoylcytidine (IV),which is then isomerized by treatment with POCl3 in ethyl acetate.
参考文献标题:
文献作者:Ishida,T.; et al.
参考来源:JP 7626884
产品链接: CAS No. 55726-45-9››