SRI-8228
6-[2-甲氧基-5-(三氟甲基)苯氨甲基]-5-甲基吡啶[2,3-d]嘧啶-2,4-二胺Chemical Name: 6-[2-Methoxy-5-(trifluoromethyl)phenylaminomethyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
CAS No. 174654-98-9
项目整合开发状态: Preclinical
项目研究机构: Southern Research Institute (Originator)
合成路线:By condensation of bromomethyl derivative (I) with aniline (II).
合成路线:By condensation of bromomethyl derivative (I) with aniline (II).
📌 参考资料/链接：
参考文献标题:Lipophilic antifolates as agents against opportunistic infections.1.Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations
文献作者:Piper,J.R.; Johnson,C.A.; Krauth,C.A.; Carter,R.L.; Hosmer,C.A.; Queener,S.F.; Borotz,S.E.; Pfefferkorn,E.R.
参考来源:J Med Chem 1996,39(6),1271