Batebulast hydrochloride, NCO-650
三壬基苯酚 Chemical Name: trans-4-Guanidinomethylcyclohexanecarboxylic acid 4-(1,1-dimethylethyl)phenyl ester hydrochloride
CAS No. 83373-31-3, 81907-78-0 (free base)
项目整合开发状态: Phase II
项目研究机构: Nippon Chemiphar (Originator)
合成路线:By esterification of trans-4-guanidinomethylcyclohexanecarboxylic acid (I) with 4-tert-butylphenol (II) using dicyclohexylcarbodiimide as condensing agent.
📌 参考资料/链接：
参考文献标题:NCO-650
文献作者:Serradell,M.N.; Castar,J.
参考来源:Drugs Fut 1984,9(8),589
📄 详细内容
合成路线:By esterification of trans-4-guanidinomethylcyclohexanecarboxylic acid (I) with 4-tert-butylphenol (II) using dicyclohexylcarbodiimide as condensing agent.
参考文献标题:Guanidinocyclohexanecarboxylic acid derivatives
文献作者:Muramatsu,M.; et al.
参考来源:BE 0891790; CH 652119; DE 3201817; FR 2498183; US 4465851
产品链接: CAS No. 83373-31-3›› 产品链接: CAS No.81907-78-0››