4-Iodopropofol
4-碘-2,6-双(1-甲基乙基)苯酚Chemical Name: 4-Iodo-2,6-diisopropylphenol
CAS No. 169255-48-5
项目整合开发状态: Preclinical
项目研究机构: Cornell University (Originator), Universit?degli Studi di Bari (Originator), Universit?degli Studi di Cagliari (Originator)
合成路线:The title compound was obtained by iodination of 2,6-diisopropylphenol (propofol) (I) employing either potassium iodide and hydrogen peroxide or iodonium chloride in HOAc.
📌 参考资料/链接：
参考文献标题:Use derivatives of 2,4-bisubstituted phenols as 5-lipoxigenase inhibitors
文献作者:Bonal,J.; et al.(Bobel246 SL)
参考来源:WO 9521610
📄 详细内容
合成路线:The title compound was obtained by iodination of 2,6-diisopropylphenol (propofol) (I) employing either potassium iodide and hydrogen peroxide or iodonium chloride in HOAc.
参考文献标题:Propofol analogues.Synthesis,relationships between structure and affinity at GABAA receptor in rat brain,and differential electrophysiological profile at recombinant human GABAA receptors
文献作者:Trapani,G.; Latrofa,A.; Franco,M.; Altomare,C.; Sanna,E.; Usala,M.; Biggio,G.; Liso,G.
参考来源:J Med Chem 1998,41(11),1846
产品链接: CAS No. 169255-48-5››