M-17055

4(1H)-喹喴酮,7-氯-2,3-二氢-1-(2-甲基苯甲酰)-,O-磺胺,钾盐(1:1)Chemical Name: 7-Chloro-1-(2-methylbenzoyl)-1,2,3,4-tetrahydroquinolin-4-one O-sulfooxime potassium salt
CAS No. 114417-20-8
项目整合开发状态: Phase III
项目研究机构: Mochida (Originator)
合成路线:The condensation of 7-chloro-1,2,3,4-tetrahydroquinolin-4-one (I) with 2-methylbenzoyl chloride (II) by means of pyridine in dichloromethane gives the corresponding acyl quinolone (III),which is then treated with hydroxylamine-O-sulfonic acid (IV) and K2CO3 to yield the target oxime.