CI-844
3-苯氧基吡啶Chemical Name: 3-Phenoxypyridine sulfate
CAS No. 2176-45-6 (free base), 66066-82-8 (HBr salt), 66066-81-7 (HCl), 66066-84-0 (methanesulfonate)
项目整合开发状态: Phase II
项目研究机构: Pfizer (Originator)
合成路线:3-Phenoxypyridine can be prepared by two different ways:1) By reaction of 3-hydroxypyridine (I) with bromobenzene (II) by means of KOH and copper bronze at 150 C.2) By reaction of 3-iodopyridine (III) with phenol (IV) by means of KOH and copper bronze at 150 C.The monosulfate salt is prepared by treating 3-phenoxypyridine with H2SO4.
📌 参考资料/链接：
参考文献标题:3-Phenoxypyridine monosulfate and a method for its production
文献作者:Butler,D.E.(Pfizer Inc.)
参考来源:BE 0861649; DE 2755016; ES 464922; FR 2392009; GB 1559918; JP 53077068; US 4128555
📄 详细内容
合成路线:3-Phenoxypyridine can be prepared by two different ways:1) By reaction of 3-hydroxypyridine (I) with bromobenzene (II) by means of KOH and copper bronze at 150 C.2) By reaction of 3-iodopyridine (III) with phenol (IV) by means of KOH and copper bronze at 150 C.The monosulfate salt is prepared by treating 3-phenoxypyridine with H2SO4.
参考文献标题:CI-844
文献作者:Owen,R.T.; Castar,J.; Serradell,M.N.
参考来源:Drugs Fut 1985,10(4),279
合成路线:3-Phenoxypyridine can be prepared by two different ways:1) By reaction of 3-hydroxypyridine (I) with bromobenzene (II) by means of KOH and copper bronze at 150 C.2) By reaction of 3-iodopyridine (III) with phenol (IV) by means of KOH and copper bronze at 150 C.The monosulfate salt is prepared by treating 3-phenoxypyridine with H2SO4.
参考文献标题:Quaternary deivation of pyridyl ethers.Onium Compound.XVI
文献作者:Renshaw,R.R.; Conn,R.C.
参考来源:J Am Chem Soc 1937,59297-301
产品链接: CAS No. 2176-45-6››