Epanolol CAS Registry Number: 86880-51-5 依泮洛尔
CAS Name: N-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxybenzeneacetamide
Additional Names: 1-(2-cyanophenoxy)-3-b-(4-hydroxyphenylacetamido)ethylamino-2-propanolPercent Composition: C 65.03%, H 6.28%, N 11.37%, O 17.32%
📌 参考资料/链接:
Literature References: Cardio-selective b1-adrenergic blocker with intrinsic sympathomimetic activity. Prepn: L. H. Smith, DE 2362568; idem, US 4167581 (1974, 1979 both to ICI). Clinical pharmacology: T. H. Pringle et al., Br. J. Clin. Pharmacol. 21, 249 (1986). Clinical pharmacokinetics: I. D. Cockshott et al., Biopharm. Drug Dispos. 11, 253 (1990). Clinical evaluation in hypertension: B. Dahlof et al., Br. J. Clin. Pharmacol. 18, 831 (1984); in angina: J. Boberg et al., Clin. Cardiol. 15, 591 (1992).
📄 详细内容
Properties: Crystals from acetonitrile, mp 118-120°.
Melting point: mp 118-120°
Therap-Cat: Antihypertensive; antianginal.
Keywords: ?Adrenergic Blocker; Antianginal; Antihypertensive; Aryloxypropanolamine Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.
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