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Rivastigmine CAS Registry Number: 123441-03-2 利凡斯的明

CAS Name: Ethylmethylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
Additional Names: (S)-N-ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate
Percent Composition: C 67.17%, H 8.86%, N 11.19%, O 12.78%

📌 参考资料/链接：
Literature References: Brain selective acetylcholinesterase inhibitor. Prepn: A. Enz, DE 3805744; idem, US 5602176 (1988, 1997 both to Sandoz); and activity: R. Amstutz et al., Helv. Chim. Acta 73, 739 (1990). Pharmacology: A. Enz et al., Prog. Brain Res. 98, 431 (1993). Clinical trial in Alzheimer's disease: M. Rösler et al., Br. Med. J. 318, 633 (1999).

📄 详细内容

Properties: [a]D20 -32.1° (c = 5 in ethanol).
Optical Rotation: [a]D20 -32.1° (c = 5 in ethanol)
Derivative Type: Hydrogen tartrate
CAS Registry Number: 129101-54-8Trademarks: Exelon (Novartis)
Percent Composition: C 53.99%, H 7.05%, N 7.00%, O 31.97%
Properties: Crystals from ethanol, mp 123-125°. [a]D20 +4.7° (c = 5 in ethanol).
Melting point: mp 123-125°
Optical Rotation: [a]D20 +4.7° (c = 5 in ethanol)
Therap-Cat: Nootropic.
Keywords: Cholinesterase Inhibitor; Nootropic.
产品链接: 123441-03-2››

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