Butenafine CAS Registry Number: 101828-21-1 布替萘芬
CAS Name: N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine
Additional Names: N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine
Percent Composition: C 87.01%, H 8.57%, N 4.41%
📌 参考资料/链接：
Literature References: Benzylamine antifungal; squalene epoxidase inhibitor. Prepn: T. Maeda et al., EP 164697; eidem, US 5021458 (1985, 1991 both to Kaken). Antifungal activity in vivo: T. Arika et al., Antimicrob. Agents Chemother. 34, 2250 (1990). Review of antifungal activity, mechanism of action, and clinical trials: R. Fukushiro et al., in Recent Progress in Antifungal Chemotherapy, H. Yamaguchi et al., Eds. (Dekker, New York, 1992) pp. 147-157. Clinical trial in treatment of athlete's foot: T. A. Syed et al., Clin. Drug Invest. 9, 393 (2000).
📄 详细内容
Derivative Type: Hydrochloride
CAS Registry Number: 101827-46-7Trademarks: Mentax (Kaken)
Percent Composition: C 78.05%, H 7.97%, N 3.96%, Cl 10.02%
Properties: Crystals from acetone + ethanol, mp 211-213°. Easily sol in methanol, ethanol, dichloromethane, chloroform. Slightly sol in water.
Melting point: mp 211-213°
Therap-Cat: Antifungal.
Keywords: Antifungal (Synthetic); Allylamines.
产品链接: 101828-21-1››