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Alprenolol CAS Registry Number: 13655-52-2 阿普洛尔

CAS Name: 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol
Additional Names: 1-(o-allylphenoxy)-3-(isopropylamino)-2-propanolPercent Composition: C 72.25%, H 9.30%, N 5.62%, O 12.83%

📌 参考资料/链接：
Literature References: b-Adrenergic blocker. Prepn: Brandstrom et al., Acta Pharm. Suec. 3, 303 (1966); NL 6605692 (1966 to AB Hassle), C.A. 66, 46214p (1967); NL 6612958 (1967 to ICI), C.A. 67, 99851w (1967). Pharmacology: Marmo, Clin. Ter. 56, 121-176 (1971). Series of articles on clinical effect in myocardial infarction: Acta Med. Scand. 1984, Suppl. 680, 1-64.

📄 详细内容

Derivative Type: Hydrochloride
CAS Registry Number: 13707-88-5
Trademarks: Apllobal (Fujisawa); Aptine (Astra); Aptol Duriles (Astra); Gubernal (Novartis); Regletin (Teikoku Zoki); Yobir (Maruko)
Percent Composition: C 63.04%, H 8.46%, N 4.90%, O 11.20%, Cl 12.40%
Properties: Crystals from ethyl acetate, mp 107-109°. LD50 in mice, rats, rabbits (mg/kg): 278.0, 597.0, 337.3 orally (Marmo).
Melting point: mp 107-109°
Toxicity data: LD50 in mice, rats, rabbits (mg/kg): 278.0, 597.0, 337.3 orally (Marmo)
Therap-Cat: Antihypertensive; antianginal; antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.
产品链接: 13655-52-2››

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