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Salmeterol CAS Registry Number: 89365-50-4 沙美特罗

CAS Name: 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
Additional Names: (±)-4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-a,a1-diolPercent Composition: C 72.25%, H 8.97%, N 3.37%, O 15.40%

📌 参考资料/链接：
Literature References: b2-Adrenergic agonist; structural analog of albuterol, q.v. Prepn: I. F. Skidmore et al., DE 3414752; eidem, US 4992474 (1984, 1991 both to Glaxo). Pharmacology: M. Johnson, Lung 168, Suppl., 115 (1990). Preliminary evaluations in asthma: A. Ullman et al., Am. Rev. Respir. Dis. 142, 571 (1990); O. P. Twentyman et al., Lancet 336, 1338 (1990). Review of pharmacology and therapeutic use: R. N. Brogden, D. Faulds, Drugs 42, 895-912 (1991).

📄 详细内容

Properties: mp 75.5-76.5°.
Melting point: mp 75.5-76.5°
Derivative Type: 1-Hydroxy-2-naphthoate
CAS Registry Number: 94749-08-3
Additional Names: Salmeterol xinafoateTrademarks: Arial (Domp?; Salmetedur (Menarini); Serevent (GSK)
Percent Composition: C 71.62%, H 7.51%, N 2.32%, O 18.55%
Properties: mp 137-138°. Freely sol in methanol; slightly sol in ethanol, chloroform, isopropanol; sparingly sol in water.
Melting point: mp 137-138°
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.
产品链接: 89365-50-4››

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