Derivative Type: Partricin A
Percent Composition: C 59.08%, H 7.90%, N 2.34%, O 30.68%
Properties: Greenish-yellow powder, mp 300° (dec). uv max (75% methanol in DMF): 232, 240, 247, 288, 342, 358, 378, 400 nm (e 33476, 32237, 22936, 15493, 58282, 76883, 102308, 89280). pKa's (70% aq DMF): 6.07, 8.91.
Melting point: mp 300° (dec)
pKa: pKa's (70% aq DMF): 6.07, 8.91
Absorption maximum: uv max (75% methanol in DMF): 232, 240, 247, 288, 342, 358, 378, 400 nm (e 33476, 32237, 22936, 15493, 58282, 76883, 102308, 89280)
Derivative Type: Partricin B
Percent Composition: C 60.14%, H 7.74%, N 2.42%, O 29.70%
Properties: Brownish-yellow powder, mp 300° (dec). uv max (75% methanol in DMF): 232, 240, 247, 288, 342, 358, 378, 400 nm (e 34761, 32826, 23174, 20594, 50207, 73392, 100425, 87558). pKa's (70% aq DMF): 6.31, 8.95. [a]D26 +87.2° (c = 0.06 in DMF).
Melting point: mp 300° (dec)
pKa: pKa's (70% aq DMF): 6.31, 8.95
Optical Rotation: [a]D26 +87.2° (c = 0.06 in DMF)
Absorption maximum: uv max (75% methanol in DMF): 232, 240, 247, 288, 342, 358, 378, 400 nm (e 34761, 32826, 23174, 20594, 50207, 73392, 100425, 87558)
Derivative Type: Complex
Properties: Amphoteric yellow crystals. uv max (ethanol): 401, 379, 359, 341 nm. Sol in DMF, DMSO, dimethyl acetamide, pyridine. Practically insol in water, common organic solvents. LD50 in mice (mg/kg): 300 orally; 0.5 i.p. (Bruzzese).
Absorption maximum: uv max (ethanol): 401, 379, 359, 341 nm
Toxicity data: LD50 in mice (mg/kg): 300 orally; 0.5 i.p. (Bruzzese)
Derivative Type: Methyl ester see Mepartricin
产品链接: 11096-49-4››