Reproterol CAS Registry Number: 54063-54-6 瑞普特罗
CAS Name: 7-[3-[[2-(3,5-Dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Additional Names: 7-[3-[(b,3,5-trihydroxyphenethyl)amino]propyl]theophyllinePercent Composition: C 55.52%, H 5.95%, N 17.98%, O 20.54%
📌 参考资料/链接：
Literature References: Theophylline deriv which has selective activity on b2 receptors. Prepn: FR M5969 (1968 to Degussa), C.A. 71, 70644c (1969). See also FR Addn. 0308 (1970 to Degussa), C.A. 78, 72216h (1973). Synthesis: K. H. Klingler, Arzneim.-Forsch. 27, 4 (1977). Toxicology: S. Habersang, ibid. 45. Series of articles on metabolism, pharmacology and clinical trials: ibid. 15-76. Other clinical studies: D. Nolte et al., Dtsch. Med. Wochenschr. 102, 619 (1977); H. Budmiger et al., Schweiz. Med. Wochenschr. 108, 1190 (1978).
📄 详细内容
Derivative Type: Hydrochloride
CAS Registry Number: 13055-82-8Trademarks: Asmaterolo (Lusofarmaco); Bronchodil (Viatris); Bronchospasmin (Viatris)
Percent Composition: C 50.76%, H 5.68%, N 16.44%, O 18.78%, Cl 8.32%
Properties: Crystals, mp 249-250°. LD50 in mice (mg/kg): 148 i.v., 10,000 orally (Habersang).
Melting point: mp 249-250°
Toxicity data: LD50 in mice (mg/kg): 148 i.v., 10,000 orally (Habersang)
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.
产品链接: 54063-54-6››