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Granisetron CAS Registry Number: 109889-09-0 格拉司琼


CAS Name: 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
Percent Composition: C 69.20%, H 7.74%, N 17.93%, O 5.12%
📌 参考资料/链接:
Literature References: Specific serotonin (5HT3) receptor antagonist. Prepn: F. D. King, EP 200444; idem, US 4886808 (1986, 1989 both to Beecham). 5HT3 receptor binding study: G. J. Kilpatrick et al., Nature 330, 746 (1987). Series of articles on pharmacology and clinical trials to prevent chemotherapy-induced emesis: Semin. Oncol. 22, Suppl. 10, 1-30 (1995).

📄 详细内容


Derivative Type: Hydrochloride
CAS Registry Number: 107007-99-8Trademarks: Kytril (SKB)
Percent Composition: C 61.97%, H 7.22%, N 16.06%, O 4.59%, Cl 10.16%
Properties: White to off-white solid, mp 290-292°. Readily sol in water at 20°.
Melting point: mp 290-292°
Therap-Cat: Antiemetic.
Keywords: Antiemetic; Serotonin Receptor Antagonist.
产品链接: 109889-09-0››