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Proxazole CAS Registry Number: 5696-09-3 普罗沙唑

CAS Name: N,N-Diethyl-3-(1-phenylpropyl)-1,2,4-oxadiazole-5-ethanamine
Additional Names: 5-[2-(diethylamino)ethyl]-3-(a-ethylbenzyl)-1,2,4-oxadiazole; propaxoline
Percent Composition: C 71.04%, H 8.77%, N 14.62%, O 5.57%

📌 参考资料/链接：
Literature References: Smooth muscle relaxant. Prepn: GB 924608; Palazzo, Silvestrini, US 3141019 (1963, 1964 both to Angelini Francesco). Pharmacology: Silvestrini, Pozzatti, Arzneim.-Forsch. 13, 798 (1963). Separation and pharmacology of the enantiomers: De Feo et al., Farmaco Ed. Sci. 26, 370 (1971). Clinical trial in cerebrovascular insufficiency: G. Esposito, M. De Gregorio, Arzneim.-Forsch. 24, 1692 (1974).

📄 详细内容

Properties: bp0.2 132°.
Boiling point: bp0.2 132°
Derivative Type: Citrate
CAS Registry Number: 132-35-4Trademarks: Flou (ELEA); Pirecin (Yoshitomi); Toness (Angelini)
Percent Composition: C 57.61%, H 6.94%, N 8.76%, O 26.69%
Properties: LD50 in rats (mg/kg): 39 i.p., 60 orally (Silvestrini, Pozzatti).
Toxicity data: LD50 in rats (mg/kg): 39 i.p., 60 orally (Silvestrini, Pozzatti)
Derivative Type: Nitrate
Properties: Crystals, mp 127-128°.
Melting point: mp 127-128°
Therap-Cat: Antispasmodic.
Therap-Cat-Vet: Antispasmodic.
Keywords: Antispasmodic.
产品链接: 5696-09-3››

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