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Fonazine CAS Registry Number: 7456-24-8 二甲替嗪

CAS Name: 10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
Additional Names: 10-(2-dimethylaminopropyl)-3-dimethylsulfamidophenothiazine; 3-dimethylsulfamido-10-(2-dimethylaminopropyl)phenothiazine; dimethothiazine; dimethiotazine; dimetiotazinePercent Composition: C 58.28%, H 6.44%, N 10.73%, O 8.17%, S 16.38%

📌 参考资料/链接：
Literature References: Serotonin inhibitor. Prepn: GB 814512 (1959 to Rhône-Poulenc). Pharmacokinetics and distribution in dog and rat: O. R. W. Lewellen, R. Templeton, Adv. Biochem. Psychopharmacol. 9, 213 (1974). Clinical evaluation in spasticity: W. B. Matthews et al., Acta Neurol. Scand. 48, 635 (1972). HPLC determn in plasma: J. Holt et al., Br. J. Clin. Pharmacol. 13, 282 (1982).

📄 详细内容

Derivative Type: Hydrochloride
Percent Composition: C 53.32%, H 6.12%, N 9.82%, O 7.48%, S 14.98%, Cl 8.28%
Properties: Crystals, dec 214°.
Derivative Type: Methanesulfonate
CAS Registry Number: 7455-39-2
Additional Names: Dimethothiazine mesylate; fonazine mesylate
Trademarks: Banistyl (M B); Bonpac (Hoei); Calsekin (Mect); Migristène (Specia); Neomestine (Taiyo); Promaquid (Rhe-Poulenc); Yoristen (Kodama)
Percent Composition: C 49.26%, H 5.99%, N 8.62%, O 16.40%, S 19.73%
Therap-Cat: Antimigraine.
Keywords: Antimigraine.
产品链接: 7456-24-8››

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