Almotriptan CAS Registry Number: 154323-57-6 阿莫曲坦
CAS Name: 1-[[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine
Additional Names: 1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidinePercent Composition: C 60.87%, H 7.51%, N 12.53%, O 9.54%, S 9.56%
📌 参考资料/链接：
Literature References: Serotonin 5HT1B/1D-receptor agonist. Prepn: D. F. Forner et al., WO 9402460; eidem, US 5565447 (1994, 1996 both to Almirall). Clinical pharmacokinetics: J. C. Fleishaker et al., Clin. Pharmacol. Ther. 67, 498 (2000). Review of pharmacology: F. Kamali, Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs 2, 197-202 (2000); of clinical studies: D. W. Dodick, Expert Opin. Pharmacother. 4, 1157-1163 (2003).
📄 详细内容
Derivative Type: Maleate
CAS Registry Number: 181183-52-8Trademarks: Almogran (Almirall); Axert (Pharmacia Upjohn)
Percent Composition: C 53.72%, H 6.65%, N 8.95%, O 23.85%, S 6.83%
Properties: White to slightly yellow crystalline powder; sol in water.
Therap-Cat: Antimigraine.
Keywords: Antimigraine; Serotonin Receptor Agonist.
产品链接: 154323-57-6››