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项目整合精选>>>Penicillin G Hydrabamine CAS Registry Number: 3344-16-9 4-硫-1-氮杂双环[3.2.0]庚烷-2-羧酸,3,3-二甲基-7-氧代-6-[(苯乙酰)氨基]-[2S-(2,5,6)]-,组成 [1R-[1(1R*,4aS*,10aR*),4a,10a]]-N,N'-双[[1,2,3,4,4a,9,10,10a-辛氢-1,4a-二甲基-7-(
Penicillin G Hydrabamine CAS Registry Number: 3344-16-9 4-硫-1-氮杂双环[3.2.0]庚烷-2-羧酸,3,3-二甲基-7-氧代-6-[(苯乙酰)氨基]-[2S-(2,5,6)]-,组成 [1R-[1(1R*,4aS*,10aR*),4a,10a]]-N,N'-双[[1,2,3,4,4a,9,10,10a-辛氢-1,4a-二甲基-7-(
Additional Names: N,N'-Bis(dehydroabietyl)ethylenediamine dipenicillin G; benzylpenicillinic acid N,N'-bis(dehydroabietyl)ethylenediamine double salt; hydrabamine penicillin G
Percent Composition: C 70.22%, H 7.96%, N 6.64%, O 10.11%, S 5.07%
📌 参考资料/链接：
Literature References: Semi-synthetic antibiotic. Prepn: L. C. Cheney, US 2812325 (1957). Pharmacology: D. W. MacCorquodale et al., Antibiot. Annu. 1954-1955, 133; M. H. Lepper, H. W. Spies, ibid. 137; A. F. DeRose et al., Antibiot. Chemother. 5, 315, 324 (1955). Purification: A. F. DeRose, US 2812326 (1957 to Abbott).
📄 详细内容
Properties: Tasteless crystals from dil methanol, dec 171-173°. [a]D25 +115.3° (c = 10 in chloroform). Solubilities determined by P. J. Weiss et al., Antibiot. Chemother.
7, 374 (1957) in mg/ml at about 28°: Water 0.075; methanol 7.3; ethanol 5.2; isopropanol 1.7; isoamyl alcohol 3.1; cyclohexane 0.115; benzene 0.60; toluene 0.39; petr ether 0.0; isooctane 0.055; carbon tetrachloride 0.50; ethyl acetate 1.65; isoamyl acetate 1.4; acetone 3.4; methyl ethyl ketone 3.65; ether 0.70.
Optical Rotation: [a]D25 +115.3° (c = 10 in chloroform)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 3344-16-9››