Amikacin CAS Registry Number: 37517-28-5 阿米卡星

📌 参考资料/链接：
Literature References: Semisynthetic aminoglycoside antibiotic derived from kanamycin A. Prepn: Kawaguchi et al., J. Antibiot. 25, 695 (1972); H. Kawaguchi, T. Naito, DE 2234315; H. Kawaguchi et al., US 3781268 (both 1973 to Bristol-Myers). Biological formation from kanamycin A: L. M. Cappelletti, R. Spagnoli, J. Antibiot. 36, 328 (1983). Microbiological evaluation: Price et al., ibid. 25, 709 (1972). Pharmacokinetics: Cabana, Taggart, Antimicrob. Agents Chemother. 3, 478 (1973). In vitro studies: Yu, Washington, ibid. 4, 133 (1973); Bodey, Stewart, ibid. 186. Pharmacology in humans: Bodey et al., ibid. 5, 508 (1974). Toxicity studies: Fujisawa et al., J. Antibiot. 27, 677 (1974). Review: K. A. Kerridge in Pharmacological and Biochemical Properties of Drug Substances vol. 1, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1977) pp 125-153. Comprehensive description: P. M. Monteleone et al., Anal. Profiles Drug Subs. 12, 37-71 (1983).