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Xanomeline CAS Registry Number: 131986-45-3 占诺美林

CAS Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine
Percent Composition: C 59.75%, H 8.24%, N 14.93%, O 5.69%, S 11.39%

📌 参考资料/链接：
Literature References: Selective muscarinic M1-receptor agonist. Prepn: P. Sauerberg, P. H. Olesen, EP 384288 (1990 to Ferrosan); eidem, US 5043345 (1991 to Novo Nordisk); eidem et al., J. Med. Chem. 35, 2274 (1992). Prepn of crystalline tartrate: L. M. Osborne et al., WO 9429303 (1994 to Novo Nordisk). Muscarinic receptor binding study: H. E. Shannon et al., J. Pharmacol. Exp. Ther. 269, 271 (1994). Pharmacology: F. P. Bymaster et al., ibid. 282. HPLC determn in plasma: C. L. Hamilton et al., J. Chromatogr. 613, 365 (1993).

📄 详细内容

Derivative Type: Oxalate
CAS Registry Number: 141064-23-5
Percent Composition: C 51.74%, H 6.78%, N 11.31%, O 21.54%, S 8.63%
Properties: Crystals from acetone, mp 148°.
Melting point: mp 148°
Derivative Type: (+)-L-Hydrogen tartrate
CAS Registry Number: 152854-19-8
Additional Names: Xanomeline tartrateTrademarks: Lomeron (Lilly); Memcor (Lilly)
Percent Composition: C 50.10%, H 6.77%, N 9.74%, O 25.95%, S 7.43%
Properties: Crystals from 2-propanol, mp 95.5°.
Melting point: mp 95.5°
Therap-Cat: Cholinergic; nootropic.
Keywords: Cholinergic; Nootropic.
产品链接: 131986-45-3››

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