Deracoxib CAS Registry Number: 169590-41-4 地拉考昔
CAS Name: 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamideTrademarks: Deramaxx (Novartis)
Percent Composition: C 51.38%, H 3.55%, F 14.34%, N 10.57%, O 12.08%, S 8.07%
📌 参考资料/链接：
Literature References: Selective cyclooxygenase-2 (COX-2) inhibitor. Prepn: J. J. Talley et al., WO 9515316; M. J. Graneto, US 5521207 (1995, 1996 both to Searle); T. D. Penning et al., J. Med. Chem. 40, 1347 (1997). Structure activity study: G. R. Desiraju et al., Molecules 5, 945 (2000). Effect in experimental synovitis in dogs: D. L. Millis et al, Vet. Ther. 3, 453 (2002); HPLC determn in plasma: S. K. Cox et al., J. Chromatogr. B 819, 181 (2005).
📄 详细内容
Properties: Light tan solid, mp 159-161°.
Melting point: mp 159-161°
Therap-Cat-Vet: Anti-inflammatory; analgesic.
产品链接: 169590-41-4››