Licostinel CAS Registry Number: 153504-81-5 6,7-二氯-5-硝基喹喔啉-2,3(1H,4H)-二酮
CAS Name: 6,7-Dichloro-1,4-dihydro-5-nitro-2,3-quinoxalinedione
Additional Names: 6,7-dichloro-5-nitro-1,4-dihydroquinoxaline-2,3-dionePercent Composition: C 34.81%, H 1.10%, Cl 25.69%, N 15.22%, O 23.19%
📌 参考资料/链接：
Literature References: Antagonist of the NMDA receptor at the glycine site. Prepn: E. Weber, J. F. W. Keana, WO 9400124 (1994); eidem, US 5622952 (1997 to Univ. Oreg; Regents Univ. Calif.); J. F. W. Keana et al., J. Med. Chem. 38, 4367 (1995). Pharmacology in vitro: R. M. Woodward et al., Mol. Pharmacol. 47, 568 (1995); in vivo: B. D. Kretschmer et al., Eur. J. Pharmacol. 331, 109 (1997). Clinical evaluation and pharmacokinetics in acute stroke: G. W. Albers et al., Stroke 30, 508 (1999).
📄 详细内容
Properties: Yellow powder, mp 342-344°.
Melting point: mp 342-344°
Therap-Cat: Neuroprotective.
Keywords: Neuroprotective; NMDA Receptor Antagonist.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 153504-81-5››