Properties: Faintly bitter crystals producing transient numbness of the tongue. mp 147-150°. pKa 8.39. uv max (water): 225, 310 nm (e 14108, 26352); (0.1N H2SO4): 229, 281, 312 nm (E1%1cm 509, 55, 76); (methanol): 226, 310 nm (e 7586, 29512); (chloroform): 308 nm (e 27542). Sol at 20° in 7.5 parts water, 40 parts alcohol; 30 parts chloroform. Practically insol in ether, benzene, acetone. The aq soln is neutral to litmus. Aq solns are stable and may be sterilized by brief boiling. LD50 i.p. in mice: 70 mg/kg (Dawes); also reported as LD50 in female mice (mg/kg): 13 i.v.; 35 s.c. (Bopp).
Melting point: mp 147-150°
pKa: pKa 8.39
Absorption maximum: uv max (water): 225, 310 nm (e 14108, 26352); (0.1N H2SO4): 229, 281, 312 nm (E1%1cm 509, 55, 76); (methanol): 226, 310 nm (e 7586, 29512); (chloroform): 308 nm (e 27542)
Toxicity data: LD50 i.p. in mice: 70 mg/kg (Dawes); also reported as LD50 in female mice (mg/kg): 13 i.v.; 35 s.c. (Bopp)
Therap-Cat: Anesthetic (local).
Therap-Cat-Vet: Anesthetic (topical).
Keywords: Anesthetic (Local).
产品链接: 136-47-0››