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Oxantel CAS Registry Number: 36531-26-7 奥克生太

CAS Name: (E)-3-[2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]phenol
Additional Names: (E)-m-[2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)vinyl]phenol; 1-methyl-1,4,5,6-tetrahydro-2-[2-(3-hydroxyphenyl)vinyl]pyrimidinePercent Composition: C 72.19%, H 7.46%, N 12.95%, O 7.40%

📌 参考资料/链接：
Literature References: Analog of pyrantel, q.v., with activity vs whipworms (Trichuris spp.). Prepn: J. W. Mc Farland, ZA 6804589 corresp to US 3579510 and US 3708584 (1968, 1971, 1973 all to Pfizer). Synthesis and evaluation in whipworm control: J. W. Mc Farland, H. L. Howes J. Med. Chem. 15, 365 (1972). Evaluation vs Trichuris in dogs: H. L. Howes, Proc. Soc. Exp. Biol. Med. 139, 394 (1972). Efficacy vs T. trichiuris in humans: E. L. Lee et al., Am. J. Trop. Med. Hyg. 25, 563 (1976); vs T. suis in swine: M. Robinson, Vet. Parasitol. 5, 223 (1979). Anthelmintic effects of combination with pyrantel pamoate: B. Sinniah, D. Sinniah, Ann. Trop. Med. Parasitol. 75, 315 (1981).

📄 详细内容

Derivative Type: Hydrochloride
Percent Composition: C 61.78%, H 6.78%, N 11.08%, O 6.33%, Cl 14.03%
Properties: Crystals from ethanol, mp 207-208°. uv max (water): 231, 274 nm (e 12700, 20100).
Melting point: mp 207-208°
Absorption maximum: uv max (water): 231, 274 nm (e 12700, 20100)
Derivative Type: Pamoate
CAS Registry Number: 68813-55-8
Additional Names: Oxantel embonateTrademarks: Telopar (Pfizer)
Percent Composition: C 71.51%, H 5.33%, N 4.63%, O 18.52%
Derivative Type: Mixture with pyrantel pamoate (1:1) see Pyrantel
Therap-Cat: Anthelmintic (Nematodes).
Therap-Cat-Vet: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).
产品链接: 36531-26-7››

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