Adefovir CAS Registry Number: 106941-25-7 阿德福韦

📌 参考资料/链接：
Literature References: Acyclic nucleoside phosphonate (ANP) analog. Prepn: A. Holy, I. Rosenberg, EP 206459; eidem, US 4808716 (1986, 1989 both to Ceskoslov. Akad. Ved); eidem, Collect. Czech. Chem. Commun. 52, 2801 (1987); of dipivoxil ester prodrug: J. E. Starrett, Jr. et al., EP 481214 (1992 to Bristol-Myers Squibb); eidem, US 5663159 (1997 to Inst. Org. Chem. Biochem. Acad. Sci. Czech Rep.; Rega). Crystal structure: C. H. Schwalbe et al., J. Chem. Soc. Perkin Trans. 1 1991, 1348. HPLC determn: P. Augustijns et al., J. Liq. Chromatogr. Relat. Technol. 19, 2271 (1996). Clinical pharmacokinetics: K. C. Cundy et al., Antimicrob. Agents Chemother. 39, 2401 (1995). Review of pharmacology and therapeutic potential: L. Naesens et al., Antiviral Chem. Chemother. 8, 1-23 (1997). Clinical trial in HIV infected patients: J. Kahn et al., J. Am. Med. Assoc. 282, 2305 (1999); in hepatitis B virus (HBV): R. J. C. Gilson et al, J. Viral Hepat. 6, 387 (1999). Resistance surveillance in HBV infections: H. Yang et al., Hepatology 36, 464 (2002).