Isofezolac CAS Registry Number: 50270-33-2 三苯唑酸
CAS Name: 1,3,4-Triphenyl-1H-pyrazole-5-acetic acidTrademarks: Sofenac (Rhe-Poulenc)
Percent Composition: C 77.95%, H 5.12%, N 7.90%, O 9.03%
📌 参考资料/链接：
Literature References: Non-steroidal anti-inflammatory agent; prostaglandin synthetase inhibitor. Prepn: C. Gueremy, C. Renault, DE 2312256; eidem, US 3984431 (1973, 1976 to Société Générale de Recherches et d'Applications Scientifiques). Pharmacology: J. Mizoule et al., Arch. Int. Pharmacodyn. 238, 305 (1979). HPLC determn in biological fluids: A. Bannier et al., J. Chromatogr. 227, 213 (1982).
📄 详细内容
Properties: Crystals from acetonitrile, mp 200°. LD50 in mice, rats (mg/kg): 215, 13 orally (Mizoule).
Melting point: mp 200°
Toxicity data: LD50 in mice, rats (mg/kg): 215, 13 orally (Mizoule)
Therap-Cat: Anti-inflammatory; antipyretic; analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives; Antipyretic.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 50270-33-2››