网站主页>>>项目整合精选>>>项目整合精选>>>Trichlormethine CAS Registry Number: 555-77-1 三(2-氯乙基)胺

Trichlormethine CAS Registry Number: 555-77-1 三(2-氯乙基)胺

CAS Name: 2-Chloro-N,N-bis(2-chloroethyl)ethanamine
Additional Names: 2,2',2''-trichlorotriethylamine; tris(b-chloroethyl)amine; trimustinePercent Composition: C 35.23%, H 5.91%, Cl 52.00%, N 6.85%

📌 参考资料/链接：
Literature References: Nitrogen mustard formerly used as a chemical warfare agent. Prepd by the action of thionyl chloride on triethanolamine: Ward, J. Am. Chem. Soc. 57, 914 (1935); US 2072348 (1937 to Hercules Powder). Improved procedure: Wilson, Tishler, J. Am. Chem. Soc. 73, 3635 (1951); Witten in Kirk-Othmer Encyclopedia of Chemical Technology vol. 7 (Interscience, New York, 1951) p 130. Clinical use in treatment of Hodgkin's disease and leukemias: L. S. Goodman et al., J. Am. Med. Assoc. 132, 126 (1946). Evaluation of carcinogenic risk: IARC Monographs 50, 143 (1990). GC determn in air: J. R. Stuff et al., J. Chromatogr. A 849, 529 (1999).

📄 详细内容

Properties: Mobile liquid. Faint odor of fish + soap. Vesicant, necrotizing irritant. Never use without appropriate gas mask. Volatility at 25° = 0.120 mg/l. d425 1.2347, mp -4°. bp15 144°. nD25 1.4925. Very slightly sol in water. Miscible with dimethylformamide, carbon disulfide, carbon tetrachloride, many other organic solvents and oils. The undiluted liq dec on standing and forms polymeric quaternary ammonium salts which are insol in the free base.
Melting point: mp -4°
Boiling point: bp15 144°
Index of refraction: nD25 1.4925
Density: d425 1.2347
Derivative Type: Hydrochloride
CAS Registry Number: 817-09-4
Trademarks: Trillekamin (Crookes)
Percent Composition: C 29.90%, H 5.44%, Cl 58.85%, N 5.81%
Properties: Crystals, mp 130-131°. Freely sol in water, sol in alcohol.
Melting point: mp 130-131°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Nitrogen Mustards.
产品链接: 555-77-1››

← 返回产品列表