Guar Gum CAS Registry Number: 9000-30-0 瓜尔豆胶

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Literature References: Mol wt about 220,000. The ground endosperms of Cyamopsis tetragonolobus (L.) Taub., Leguminosae which is cultivated in India as livestock feed. The water soluble fraction (85%) of guar flour is called guaran which consists of linear chains of (1®4)-b-D-mannopyranosyl units with a-D-galactopyranosyl units attached by (1®6) linkages. Ratio of D-galactose to D-mannose is 1:2. Effect on lipid metabolism: D. J. A. Jenkins et al., Br. Med. J. 2, 1555 (1979); on glucose and lipid levels in diabetic and healthy volunteers: U. Smith, G. Holm, Atherosclerosis (Shannon, Ire.) 45, 1 (1982); on renal tumors in diabetic rats: B. C. Chin et al., Biomed. Res. 5, 273 (1984). As source of fiber in patients with non-insulin dependent diabetes: M. E. McIvor et al., Am. J. Clin. Nutr. 41, 891 (1985). Toxicology studies: S. L. Graham et al., Food Cosmet. Toxicol. 19, 287 (1981). Comprehensive monograph: F. Smith, R. Montgomery, The Chemistry of Plant Gums and Mucilages (Reinhold, New York, 1959) 627 pp. Review: Goldstein et al. in Industrial Gums, R. L. Whistler, Ed. (Academic Press, New York, 2nd ed., 1973) p 303-321. Comprehensive description: K. Yu et al., Anal. Profiles Drug Subs. Excip. 24, 243-276 (1996).