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Tramazoline CAS Registry Number: 1082-57-1 曲马唑啉

CAS Name: 4,5-Dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine
Additional Names: 2-[(5,6,7,8-tetrahydro-1-naphthyl)amino]-2-imidazoline
Percent Composition: C 72.53%, H 7.96%, N 19.52%

📌 参考资料/链接：
Literature References: a-Adrenergic agonist. Prepn: Berg, DE 1191381; DE 1195323 (both 1965 to Thomae), C.A. 63, 8373c; 13274d (1965). Pharmacology and toxicity data: R. Engelhorn, H. Klupp, Arzneim.-Forsch. 12, 971 (1962). Activity studies: Sachsenröder et al., ibid. 22, 392 (1972).

📄 详细内容

Properties: Crystals from isopropanol, mp 142-143°.
Melting point: mp 142-143°
Derivative Type: Hydrochloride monohydrate
CAS Registry Number: 3715-90-0Trademarks: Biciron (Basotherm); Ellatun (Basotherm); Rhinaspray (Boehringer, Ing.); Rhinogutt (Thomae); Rhinospray (Thomae); Rinogutt (Boehringer, Ing.); Towk (Tanabe)
Percent Composition: C 57.88%, H 7.47%, N 15.58%, Cl 13.14%, O 5.93%
Properties: Crystals from alc + ether or acetone + ether, mp 172-174°. Sol in water. LD50 orally in mice: 195 mg/kg (Engelhorn, Klupp).
Melting point: mp 172-174°
Toxicity data: LD50 orally in mice: 195 mg/kg (Engelhorn, Klupp)
Therap-Cat: Decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.
产品链接: 1082-57-1››

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