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Pholedrine CAS Registry Number: 370-14-9 甲羟苯丙胺

CAS Name: 4-[2-(Methylamino)propyl]phenol
Additional Names: p-hydroxy-N,a-dimethylphenethylamine; b-(p-hydroxyphenyl)isopropylmethylamine; a-(p-hydroxyphenyl)-b-methylaminopropane; p-hydroxy-N-methylbenzedrinePercent Composition: C 72.69%, H 9.15%, N 8.48%, O 9.68%

📌 参考资料/链接：
Literature References: a-Adrenergic agonist. Prepd from p-methoxybenzyl methyl ketone: FR 822422, GB 482414, DE 674753 (1937, 1938 and 1939 to Knoll); Hildebrandt and Hildebrandt, Freese, DE 665793 and DE 767161 (1938 and 1951 to Knoll). Synthesis: Savitskii, Makhnenko, J. Gen. Chem. USSR 10, 1819 (1940); Buzas, Dufour, Bull. Soc. Chim. Fr. 1950, 139. Toxicity data: Lindner, Arch. Exp. Pathol. Pharmakol. 188, 675 (1938).

📄 详细内容

Properties: Crystals from methanol, mp 162-163°. Acrid, burning taste. Alkaline reactions. Slightly sol in water. Sol in alcohol, ether; readily sol in dil acids.
Melting point: mp 162-163°
Derivative Type: Sulfate
CAS Registry Number: 6114-26-7
Trademarks: Paredrinol (SK F); Pulsotyl (Chinoin); Veritol (Knoll)
Percent Composition: C 56.05%, H 7.53%, N 6.54%, O 22.40%, S 7.48%
Properties: Crystals, dec 320-323°. Sol in water. LD s.c. in rats: 500 mg/kg (Lindner).
Toxicity data: LD s.c. in rats: 500 mg/kg (Lindner)
Therap-Cat: Antihypotensive.
Therap-Cat-Vet: Circulatory stimulant.
Keywords: a-Adrenergic Agonist; Antihypotensive.
产品链接: 370-14-9››

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