Derivative Type: Hydrochloride
CAS Registry Number: 550-99-2
Trademarks: Ak-Con (Akorn); Albalon (Allergan); Clera (Person Covey); Coldan; Iridina Due (Montefarmaco); Naphcon (Alcon); Niazol; Opcon (Bausch Lomb); Privine (Novartis); Rhinantin; Rhinoperd; Sanorin; Sanorin-Spofa; Strictylon
Percent Composition: C 68.15%, H 6.13%, N 11.35%, Cl 14.37%
Properties: Bitter crystals, mp 255-260°. uv max (ethanol): 223, 270, 280, 287, 291 nm (E1%1cm 3622, 239, 286, 196, 198). pKa (25℃) 10.35 ±0.02, (35℃) 10.13 ±0.02, (45℃) 9.92 ±0.03. pKa (25℃) 10.35 ±0.02, (35℃) 10.13 ±0.02, (45℃) 9.92 ±0.03. Freely sol in water (40 g dissolve in 100 ml) and in alcohol. Slightly sol in chloroform. Insol in benzene, ether. A 1% aq soln has a pH of ~6.2. LD50 s.c. in rats: 385 mg/kg (Gylfe).
Melting point: mp 255-260°
pKa: pKa (25℃) 10.35 ±0.02, (35℃) 10.13 ±0.02, (45℃) 9.92 ±0.03; pKa (25℃) 10.35 ±0.02, (35℃) 10.13 ±0.02, (45℃) 9.92 ±0.03
Absorption maximum: uv max (ethanol): 223, 270, 280, 287, 291 nm (E1%1cm 3622, 239, 286, 196, 198)
Toxicity data: LD50 s.c. in rats: 385 mg/kg (Gylfe)
Therap-Cat: Adrenergic (vasoconstrictor); decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.
产品链接: 835-31-4››