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Tenidap CAS Registry Number: 120210-48-2 替尼达普

CAS Name: (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide
Additional Names: 5-chloro-2,3-dihydro-2-oxo-3-(2-thienylcarbonyl)-1H-indole-1-carboxamide; 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamidePercent Composition: C 52.42%, H 2.83%, Cl 11.05%, N 8.73%, O 14.96%, S 10.00%

📌 参考资料/链接：
Literature References: Inhibitor of 5-lipoxygenase and interleukin-1 (IL-1) activity. Prepn: S. B. Kadin, EP 156603; idem, US 4556672 (both 1985 to Pfizer). Effect on 5-lipoxygenase activity in vitro: K. Fogh et al., Arch. Dermatol. Res. 280, 430 (1988). Effect on IL-1 activity in patients with rheumatoid arthritis: B. McDonald et al., Arthritis Rheum. 31, Suppl., S52 (1988). Clinical evaluation: P. Katz et al., ibid. S52.

📄 详细内容

Properties: Fluffy, yellow crystals from acetic acid, mp 230° (dec).
Melting point: mp 230° (dec)
Derivative Type: Sodium salt
CAS Registry Number: 119784-94-0Percent Composition: C 49.06%, H 2.35%, Cl 10.34%, N 8.17%, Na 6.71%, O 14.00%, S 9.36%
Properties: Crystals from methanol-isopropanol, mp 237-238°.
Melting point: mp 237-238°
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); 5-Lipoxygenase Inhibitor.
产品链接: 120210-48-2››

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