网站主页>>>项目整合精选>>>项目整合精选>>>Guanazodine CAS Registry Number: 32059-15-7 2-(氮杂环辛烷-2-基甲基)胍硫酸盐

Guanazodine CAS Registry Number: 32059-15-7 2-(氮杂环辛烷-2-基甲基)胍硫酸盐

CAS Name: [(Octahydro-2-azocinyl)methyl]guanidine
Additional Names: a-guanidinomethylheptamethylenimine; 1-azacyclooct-2-ylmethylguanidine
Percent Composition: C 58.66%, H 10.94%, N 30.40%

📌 参考资料/链接：
Literature References: Hypotensive agent, related structurally to guanethidine. Prepn of the sulfate salt: J. Rakoczi et al., HU 155990; eidem, US 3856778 (1969, 1974 both to EGYT). Pharmacokinetics in man: T. Past et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 8, 111 (1973). General pharmacology: H. Iwata et al., Oyo Yakuri 14, 235 (1977), C.A. 88, 16070 (1977). Analytical study: E. Zollner-Ivan, Acta Pharm. Hung. 48, 76 (1978). Clinical studies in hypertension: S. Dobi et al., Ther. Hung. 28, 60 (1980); Z. Herpai et al., ibid. 181.

📄 详细内容

Derivative Type: Sulfate monohydrate Trademarks: Calnegyt (Toyo Jozo); Sanegyt (EGYT)
Percent Composition: C 35.99%, H 8.05%, N 18.65%, S 10.67%, O 26.63%
Properties: White crystals from water, mp 239-241°. LD50 in mice (mg/kg): 2450 orally, 700 s.c., 165 i.v. (Rakoczi, 1974).
Melting point: mp 239-241°
Toxicity data: LD50 in mice (mg/kg): 2450 orally, 700 s.c., 165 i.v. (Rakoczi, 1974)
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Guanidine Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 32059-15-7››

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